http://2.bp.blogspot.com/_FZe5zyi_mHA/SZyD
Faz6AmI/AAAAAAAAAFk/CNH3YCYL_6c/s400/F
ormula+general+de+los+amino%C3%A1cidos.p
ng
http://copepodo.files.wordpress.com/2010/11
/amino-acid-chart.jpg
http://upload.wikimedia.org/wikipedia/comm
ons/6/6d/Peptidformationball.svg
http://themedicalbiochemistrypage.org/i
mages/peptidebond.jpg
http://www.ehu.es/biomoleculas/peptidos/jpg/resona2.gif
http://upload.wikimedia.org/wikipedia/comm
ons/6/6f/Calmodulin.png
http://www.efn.u
ncor.edu/dep/bio
logia/intrbiol/ma
cromoleculas/alfa
3.gif
http://2.b
p.blogspo
t.com/_Z
Y7jvxGDs
GI/Shm3d
BzGWkI/A
AAAAAAA
AAs/Ai98
m0jMemc
/s320/heli
ce+A+co
mpleja.gif
http://cnho.files.w
ordpress.com/201
0/04/helicealfa1.png?w=439
&h=503
http://1.bp.blogspot.com/_iTcZbbl8vBQ/TLxg
TJU7u5I/AAAAAAAAAFQ/a3vECfgdBDQ/s640
/Alfa+helice.gif
http://www.ehu.es
/biomoleculas/prot
einas/jpg/beta_alf
a_beta.jpg
http://www.bionova.org.es/biocast/document
os/figura/figtem08/figurat0813.jpg
http://www.u
m.es/molecul
a/grapr/beta
hoj1.gif
http://2.bp.blogspot.com/b8cEwsRHSIY/Tk5LgpFa1mI/AAAAAAAAEKY
/3I2nTWcYXFQ/s1600/hojas+beta+paralela
s+y+antiparalelas.jpg
http://www2.udec.cl/~
jmartine/img00080.gif
http://www.biorom.uma.
es/contenido/av_biomo/
FigT3/Fig3_11m.gif
http://www.uib.
es/facultat/cien
cies/prof/josefa.
donoso/campus
/modulos/mod
ulo3/beta1.jpg
http://institutomodernoamericano.edu.co/moodle/grados/undecimo/contenido/qui_11/jpg/plegantipara.gif
http://bifi.es/~jsa
ncho/estructura
macromoleculas/
6Proteinasglobul
ares/barrilab(TIM
).JPG
http://upload.
wikimedia.org/
wikipedia/com
mons/thumb/3
/3f/8tim_TIM_
barrel.png/300
px8tim_TIM_barr
el.png
http://www.biorom.uma.es/contenido/a
v_biomo/FigT3/Fig3_17.gif
http://thurj.org/wpcontent/uploads/2011/01/thurj2-1ebrahim-f1.png
http://www.biog1445.org/media/fibroin.jpg
http://www.scq.ubc.ca/biomimicrybimimetics-general-principles-and-practical-examples/
http://www.pnas.org/content/103/33/12285/
F1.large.jpg
http://web.mit.edu/3.082/www/team1_f02/pi
ctures/collagenstructure.jpg
http://www.biog1445.org/media/collagen.jpg
http://www.sigmaaldrich.com/content/dam/si
gma-aldrich/lifescience/metabolomics/enzymeexplorer/collagen.gif
http://ww
w.vetmed.
vt.edu/ed
ucation/cu
rriculum/v
m8054/La
bs/Lab5/I
MAGES/C
OLLAGEN
%20COMP
OSITE%20
copy.JPG
http://www.arserrc.gov/ctmi/1948collagen.gif
http://www.leeds.ac.uk/her
itage/Astbury/Mozarts_Hair
/keratin.jpg
http://2.bp.blogspot.com/-XL35XE7KZ4/Ub5Faq07KMI/AAAAAAAAAjE/6zs4bXQzxs/s1600/Inverto-Hair-Structure.jpg
http://www.imbjena.de/~rake/Bioinformatics_W
EB/gifs/keratin.gif
http://intranet.td
mu.edu.ua/data/k
afedra/internal/i_
nurse/classes_stu
d/en/BSN(4y)/2%20year/Bio
chemistry/01%20S
tructure%20of%20
proteins,%20meth
ods%20of%20its%
20determination.fi
les/image043.jpg
http://bifi.es/~jsancho/estructuramacromolec
ulas/5Proteinasfibrosas/queratina.gif
http://4.bp.blogspot.com/x2I9gHYD0tA/Ty0l9RzXkvI/AAAAAAAAE5Q/UgT
ppuDcv_c/s1600/queratina.jpg
http://www.biorom.uma.es/contenido/av_bio
mo/FigT3/Fig3_13.gif
http://www.um.es/molecula/sb
qpr08.htm
http://upload.wikim
edia.org/wikipedia/c
ommons/2/22/Cysti
ne-skeletal.png
http://2.bp.blogspot.com/_1leJBKfzPo/UEIkfYFQ5fI/A
AAAAAAAA0Y/mEKJI1E5Qr
M/s1600/mioglobinaI.JPG
http://piruvata.blogs
pot.com.es/2013/08/
mioglobina.html
http://proteinas-biologia.blogspot.com.es/
http://www2.udec.cl/~lilherna/imagenes2/bet
alactamsesa.gif
http://www.fisican
et.com.ar/biologia/
introduccion_biolo
gia/ap1/aminoacid
os_y_proteinas04.j
pg
http://themedicalbioche
mistrypage.org/images/h
emoglobin.jpg
http://upload.wikime
dia.org/wikipedia/co
mmons/0/05/Hemogl
obina_r.JPG
http://piziadas.com/2012/05/visualizacion-deproteinas-con-blender-wallpaperhemoglobina.html
http://personales.ya.com/geopal/biologia_2b/
unidades/imagenes/tema1/desnatura.gif
http://1.bp.blogspot.com/V2vQrkJJjyw/UIbOJ0hJNuI/AAAAAAAAAAs/5gU1qn0RHc/s1600/p0316.gif
http://2.bp.blogspot.com/UzAoCSjHeEM/UXSfMZJB3WI/AAAAAAAAAA8/
Rl3aCVahWJc/s640/eggs_protein_refolding_v1.
jpg
http://cdavies.files.
wordpress.com/200
8/03/egg-proteincoagulation-5-inwidth.jpg
http://elte.prompt.hu/sites/default/files/tanan
yagok/practical_biochemistry/images/5f5c75c
a.jpg
http://www.tulane.edu/~biochem/med/am.gif
http://www.sigmaaldrich.
com/lifescience/metabolomics/en
zyme-explorer/enzymereagents/casein.html
http://www.tul
ane.edu/~bioc
hem/med/phs
ol.gif
http://www.natur
e.com/nature/jour
nal/v465/n7300/i
mages/nature091
05-f2.2.jpg
http://www.nature.com/nature/journal/v497/
n7451/fig_tab/nature12220_F1.html
http://commons.wikimedia.org/wiki/File:Phylo
genetic_tree_based_on_the_N_protein_seque
nces_of_selected_paramyxoviruses..png
N protein
sequences of
selected
paramyxoviruses
http://www.evolutionarymodel.com/CH_80.jpg
http://2.bp.blogspot.com/hqUUNis6epg/UQqnXtjsseI/AAAAA
AAAAN8/NPsJd1y0fKg/s1600/clara
+huevo.jpg
http://sportswiki.ru
/images/5/53/Colla
gen.gif
http://bioclinicaho
y.wikispaces.com/f
ile/view/insulina_(
2).jpg/236000426/
insulina_(2).jpg
http://2.bp.blogspo
t.com/-ZtyBgHn56s/UPOJY2ohvcI/
AAAAAAAAADA/vYg
0oiYWTSk/s400/315.gif
http://academic.brooklyn.cuny
.edu/biology/bio4fv/page/unisym-antiport012.JPG
http://upload.wikimedia.org/
wikipedia/commons/thumb/d
/d4/Anticuerpo.svg/255pxAnticuerpo.svg.png
http://4.bp.blogspot.com/mLM76JOhXDo/Ty6ukl2PwI/AAAAAAAABWs/NGJLHDM37
Cg/s1600/Bandas+Musculares.jpg
http://upload.wikimedia.org/wikipedia/commons/t
humb/2/24/Induced_fit_diagram.svg/648pxInduced_fit_diagram.svg.png
http://alevelnotes.com/content_images/i65_e
nzyme.gif
http://www.saburchill.com/IBbiology/chapters
01/images/040207028.jpg
http://naribiochemwiz007.files.wordpress.com
/2013/04/lockandkey.gif
http://readanddige
st.com/wpcontent/uploads/2
012/11/activesite.jpg
http://www2.estrell
amountain.edu/fac
ulty/farabee/biobk/
indfit.gif
http://plantphys.info/plant_physiology/images
/enztemprate.gif
http://www2.estrellamountain.edu/faculty/far
abee/biobk/enzpH.gif
ECUACIÓN DE MICHAELIS-MENTEN
Cuando Vo es 1/2 de Vmax:
1/2 Vmax = Vmax [S] / Km + [S]
1/2 = [S] / Km + [S]
Km + [S] = 2 [S]
Km = 2[S] - [S]
Km = [S]
http://www.ucl.ac.uk/~ucbcdab/enzass/image
s/subs5.png
ECUACIÓN DE LINEWEABER-BURK
(Transformación de L-B de la
ECUACIÓN DE MICHAELIS-MENTEN)
Se obtiene una ecuación LINEAL, mucho más cómoda de manejar
PENDIENTE
ORDENADA
EN EL
ORIGEN
http://upload.wikimedia.org/wikipedi
a/commons/thumb/7/77/Comp_inhi
b.png/300px-Comp_inhib.png
http://3.bp.blogspot.com/_Fy89RUq74S4/TKk3
huwrmnI/AAAAAAAAAE0/uOr7YAf6Muc/s1600
/inhibicion+enzim%C3%A1tica.jpg
http://gsdl.bvs.sld.cu/greenstone/collect/prelic
in/index/assoc/HASH014a.dir/fig12a06.png
http://2.bp.blogspot.com/4i8efkWVYs4/TnZLlpyRMUI/AAAAAAAAAMg/d
Sj6bRcNA80/s1600/Inhibicion+no+competitiva
.JPG
http://www.
elergonomist
a.com/biolog
ia/biof51.JPG
http://tertuliadeamigos.
webcindario.com/image
0322.jpg
http://www.oocities.org/pelabzen/inhnocomp.
gif
http://tertuliade
amigos.webcind
ario.com/image0
302.jpg
http://depa.fquim.un
am.mx/proteinas/we
bprobs/solukinprob1
0a.gif
http://www.bionova.org.es/biocast/document
os/figura/figtem14/figurat1411.jpg
http://www.oocities.org/pelabzen/inhincomp.
gif
Regulación
alostérica
http://images.tutorvista.com/cont
ent/cellularmacromolecules/allostericinhibition-process.jpeg
http://classroom.sdmesa.edu/eschmid/Lab5B8.jpg
http://www.slides
hare.net/profesor
jano/enzimasalostericos
http://www.abcte.org/files/previews/biology/
BioMod%203%5B1%5D.3%20allosteric.jpg
http://www.monografias.co
m/trabajos85/enzimasreguladoras-o-enzimasalostericas/image002.jpg
http://upload.wikim
edia.org/wikipedia/
commons/thumb/9
/96/PDB_1gqi_EBI.j
pg/400pxPDB_1gqi_EBI.jpg
http://upload.wikime
dia.org/wikipedia/co
mmons/thumb/8/8b/
PDB_1x9f_EBI.jpg/350
px-PDB_1x9f_EBI.jpg
http://web.sls.hw.a
c.uk/teaching/Dere
k_J/A13MM1web/Lectures/files/
allosteric_regulatio
n/files/1_1.jpg
http://web.usal.es/
~evillar/images/fosf
orilacion.jpg
http://web.usal.es/
~evillar/images/fos
forilacionglucogen
ofosforilasa.jpg
http://www.genomasur.com/
BCH/BCH_libro/imagenescap
_12/21.JPG
Sitios altamente recomendables para ampliar información sobre enzimas alostéricas:
http://www.slideshare.net/juanfcoopazovaldes/enzimas-vo-v
http://www.slideshare.net/profesorjano/enzimas-alostericos
http://www.slideshare.net/cuentadropbox101/regulacin-alostrica
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Diapositiva 1