The National Kidney Foundation’s
Kidney Early Evaluation ProgramTM
Essex-Passaic Wellness Coalition
March 24, 2014
Ellen H. Yoshiuchi, MPS
Division Program Director
National Kidney Foundation
Serving Greater New York
Kidney Early
Evaluation ProgramTM
10 Year Anniversary
KEEP Objectives
Identify those at  risk for CKD using inclusion criteria:
Hypertension and/or Diabetes or family history of
HTN, DM or CKD in first order relatives.
Encourage participants at  risk to seek
further medical evaluation.
Develop a referral network, such as free health clinics, for the
uninsured identified as being at  risk for CKD.
Develop a referral network of specialists for patients identified as
being at  risk for kidney disease.
KEEP Objectives
• To empower individuals to prevent or
delay the onset of CKD or renal failure
through education and appropriate
disease management!
Chronic Kidney Disease is a
Public Health Problem!
Rate of Kidney Disease Jumps by 30%
Chronic Kidney Disease is a
Public Health Problem!
The devastating consequences of CKD
are End Stage Renal Disease (ESRD),
which requires dialysis or
transplantation, or leads to
cardiovascular disease & death.
CKD is a Public Health Problem
• Early screening, diagnosis, and treatment
should delay or prevent ESRD.
• 26 Million Americans have CKD. Most don’t
know it.
• 73 Million Americans have HTN and/or DM.
• CKD is a worldwide public health problem.
KDOQI CKD Evaluation, Classification
and Stratification (2002)
• Defined 2 independent criteria for CKD:
• Glomerular filtration rate (GFR) <60 ml/min per 1.73m2 for ≥3
• Presence of kidney damage [structural/functional/pathological
abnormality; markers (i.e., albuminuria)] for ≥3 months
• Classified CKD by severity according to GFR
• Provided a common language for kidney disease that would:
• Facilitate new research
• Provide clinicians with a stage-specific clinical action plan
• Provide a framework for developing a public health approach
toward resolution
KDOQI CKD Evaluation, Classification
and Stratification (2002)
Concerns with KDOQI Definition and
Classification (2002)
• New information on albuminuria and GFR and their
association with mortality has become available
since publication of the KDOQI CKD definition and
• Increased recognition of limitations of the CKD
definition and classification initiated debate that:
• Reflects changing knowledge
• Provides opportunities for improvement
Definition of CKD
Identical to 2002
Classification of CKD
It is recommended that CKD be classified by:
• Cause
• GFR category
• Albuminuria category
• Referred to as “CGA Staging”
Represents a revision of the previous CKD
guidelines, which included staging only by level
of GFR
New Albuminuria Emphasis
• Most Family Physicians
perform some type of
office urine test.
• 90% perform a manual
urine dipstick test.
• 53% perform an
automated dipstick test.
• 58% perform an officebased urine microscopic
American Academy of Family Physicians. Practice Profile II Survey. November 2009
Criteria for CKD
• Glomerular filtration rate (GFR) <60 ml/min/1.73 m2
• GFR is the best overall index of kidney function in health and
• The normal GFR in young adults is approximately 125
ml/min/1.73 m2.
• GFR <15 ml/min/1.73 m2 is defined as kidney failure
• Can be detected by current estimating equations for GFR
based on serum creatinine or cystatin C (estimated GFR) but
not by serum creatinine or cystatin C alone
• Decreased eGFR can be confirmed by measured GFR, if
3 Levels of Prevention in CKD
Primary – Prevent the development of CKD in the
population at risk with Diabetes and/or Hypertension.
Secondary – Prevent the progression of CKD (loss of
kidney function over time) and prevent or delay CKD
Tertiary – Prevent adverse outcomes in those with
chronic kidney failure treated with dialysis or kidney
transplantation by optimizing care.
Am J Kidney Dis 2009:53:522-535
Conceptual Model of CKD: Continuum of Development,
Progression and Complications of CKD
Each Arrow is a Target for Strategies to Improve Outcomes!
Referral to Nephrology by
CKD Stage
Primary Goals of CKD Care
• To prevent the progression of CKD to ESRD
• To prevent Cardiovascular Events & Death
Heart Attacks
Congestive Heart Failure
Sudden Cardiac Death
Did You Know?
1 in 3 American adults is at high risk
for developing kidney disease
1 in 9 American adults has kidney
disease and most don’t know it
Early detection and treatment
can slow or prevent the
progression of kidney disease
Kidney disease kills over
90,000 Americans every year
What You Will Learn Today
What kidneys do
Why kidneys are important
to your health
What kidney disease is
Who is at risk
Actions you can take to
protect your kidneys
• KEEP is a free public health screening program.
• It was initiated in New York City by the National Kidney
Foundation in August of 2000.
• Screenings were held in all areas of the US by local
National Kidney Foundation divisions or affiliates.
• Over 180,000 people were screened as of 6/30/13.
• Visit for more information.
Criteria to Participate In KEEP
Anyone age 18 or older with one or more of
the following risk factors:
• History of diabetes
• History of high blood pressure
• Family history in first order relatives of
diabetes, high blood pressure and/or
kidney disease
Six Screening Stations
• Station One – Registration: Participant
receives paperwork packet
• Station Two – Screening Questionnaire &
Informed Consent: Filled out by a
professional volunteer
• Station Three – Physical Measurements:
Height, weight, waist circumference &
blood pressure
Six Screening Stations
• Station Four – Urine & Blood Testing
• Station Five – Clinician Consultation:
Interview with a physician, nurse
practitioner or physician assistant
• Station Six – Screening Review:
Participants receive copy of informed
consent & test results
KEEP Screening Evaluation
Medical history: DM, HTN, CVD, CKD
Blood pressure
Height and weight
Waist circumference
Body mass index (BMI)
Blood glucose measurement
Serum creatinine
KEEP Screening Evaluation
• Albumin to Creatinine Ratio
• eGFR
• A1C for elevated glucose or self-reported
• Total Cholesterol:
HDL, LDL, Triglycerides
• For eGFR<60 ml/min
Calcium, Phosphorus & PTH
 Not affected by short-term fluctuations in blood
glucose levels
 Reliable measurement of blood glucose
concentrations over the prior 6 to 8 weeks
• <7% of total hemoglobin
• > 7% is an indication of
increased blood sugar levels
Waist Circumference
High Risk Groups
• Women
with a waist
circumference of more
than 35 inches
• Men with a waist
circumference of more
than 40 inches
Blood Pressure Classification
KEEP uses the Blood Pressure Classifications according to The 7 th National Report Guidelines on
Prevention, Detection, Evaluation & Treatment of High Blood Pressure from the National Heart, Lung
& Blood Institute of the National Institutes of Health, referred to as JNC 7.
BP Classification
SBP mmHg
DBP mmHg
Stage 1
Stage 2
Blood Glucose Guidelines
American Diabetes Association (ADA) 2008
Criteria for the Diagnosis of Diabetes Mellitus
Normal Fasting Glucose
FPG <100 mg/dl
Impaired Fasting Glucose
FPG 100–125 mg/dl
Provisional Diagnosis of Diabetes
FPG >126 mg/dl
(The diagnosis must be confirmed. The KEEP consultant would recommend follow-up
testing & review by the participant’s primary care provider.)
Follow Up after the Screening
• 2 to 3 days: Participants with critical lab results are
called by dedicated bilingual (Spanish/English) staff.
• 3 to 4 weeks: All screening results are mailed to
participants and their physicians if participants wish to
have their doctor receive a report.
• 2 to 3 months: A follow up survey is mailed out &
participants will be called if the survey is not received.
• 12 months: Invitations are sent by mail, phone or email to attend an annual screening.
KEEP in Greater New York
9 Years/96 Screenings
2/1/2004 to 4/1/2013
• 8175 attended the screenings.
• 7373 met inclusion criteria & completed the
• 2148 were repeat participants.
• Breakdown by gender:
34.98% (2579)
Female: 64.91% (4786)
Of the 5967 who learned
of a new problem…
• 3075 learned they may have kidney disease:
• 763 learned they may have diabetes:
• 861 learned they may have hypertension:
• 1268 learned they may have high cholesterol:
5461 (74.07%) individuals were aware
of a pre-existing condition.
kidney disease:
high cholesterol:
Breakdown by Race & Ethnicity
African American: 2355
Native American:
Pacific Islander:
Ethnicity—Hispanic: 1100
Breakdown by Age Group
18 to 25:
26 to 35:
36 to 45: 1,035
46 to 55: 1,734
56 to 65: 1,927
Over 65: 1,979
Who is coming to KEEP?
• 6511 (88.31%) have a physician.
• 5282 (71.64%) have health insurance.
• 2719 (36.88%) request that a report be sent
to their doctor.
• Of 7274 with reported BMI:
Overweight: 2458 33.79%
2490 34.23%
Follow-Up Survey
• 2333 (31.64%) responded!
• Of these, 71.50% reported seeing a physician
• Of these, 10.97% had a doctor confirm that
they had kidney disease.
• Of these, 90.61% indicated they were willing
to participate in another screening.
CentraState Medical Center
September 16, 2011
Trinitas Regional Medical Center
October 18, 2011
New Jersey KEEP
Total screened: 1819
1 Nutley
1 Montclair
1 Sparta
1 East Orange
1 Toms River
1 Clifton
1 Paterson
New Jersey KEEP
6 Elizabeth
5 Freehold
5 Newark
3 Lakewood
New Jersey KEEP ‘04 through ‘12
• 628
• 1,191
• 461
• 991
• 155
• 193
• 370
(20.34% )
Other Race
New Jersey KEEP ‘04 through ‘12
Breakdown of individuals that learned of a new
• 152 (8.36%) learned they may have diabetes.
• 199 (10.94%) learned they may have hypertension.
• 278 (15.28%) learned they may have high
• 694 (38.15%) learned they may have kidney disease.
New Jersey KEEP ‘04 through ‘12
1,668 (91.70%) indicated that they have a
1,372 (75.43%) indicated that they have
906 (49.81%) requested that their report be
sent to their doctors.
795 (43.71%) responded to the survey.
595 (74.84%) who responded to the
follow- up survey reported seeing a doctor.
Key Programs and Initiatives
of the
kidney and
kidney disease
Prevent CKD in
at-risk population;
prevent progression
of early stage CKD
in early stage patients
Promote optimal
treatment by
offering education
to patients, caregivers
and healthcare
PROGRAM FOCUS: EDUCATING Primary Care Provider’s (PCP)
Research shows that early detection and evidence-based treatment can prevent or delay the onset of
chronic kidney disease and its adverse outcomes, including cardiovascular disease and kidney failure.
A recent Multi-Site Cross Sectional NKF Study enrolled 460 primary care practitioners to determine
the prevalence of CKD overall and by stage in patients with type 2 Diabetes within the primary care
setting, based on the use of eGFR calculations and urinary protein excretion (albuminuria).
Of the 9,307 patients in the study, 5036 (54.1%) had Stage 1-5 CKD based on eGFR and albuminuria;
however, only 607 (12.1%) of those patients were identified as having CKD by their clinicians.
Clinical practice guidelines on chronic kidney disease exist, findings from two recent studies demonstrate
that a large number of PCPs are not aware of the National Kidney Foundation’s clinical practice
guidelines for the evaluation and staging of CKD.
- CME Symposia at NKF Spring Clinicals April 2013: Practical CKD Knowledge
for Primary Care Providers
- Enduring Web Based CME program for PCP’s and other educational tools
KEEP Healthy
For the general public
Risk survey
Height & weight measurement
Body mass index (BMI)
Blood pressure check
Consultation with a clinician
Over the age of 18
Programs for Patients
NKF Cares
• Patient information help line to answer
questions & address concerns
• For any CKD, dialysis or transplant patient
• Staffed daily by social workers & information
specialists for the majority of the day
• Toll-free number: 1-855-653-2273
Family Talk
• An informational packet to help patients talk
to their families about kidney disease and its
connection to diabetes and high blood
• Includes booklets with basic information on
CKD, Kidney Risk Quizzes, bracelets and
stickers to distribute to the family
Family Talk
The “Family Talk” can take place in several ways:
Talking one-on-one with family members at risk
for CKD in person, via telephone or email
Having a health discussion together with several
family members
Evaluation forms for patients and the social
Pilot in dialysis centers
Kidney Community Educators
• Volunteers trained to go into the community to
present “Your Kidneys & You”
• Trained live or via Webinar
• Receive a volunteer training manual, educational
materials on kidneys & kidney disease
• Flash drive with presentation slides & training slides
• Documentation includes an agreement letter, sign-in
sheets, participant evaluation & presenter evaluation
World Kidney Day!
• Protect & Prevent on World Kidney Day:
Information on the NKF Web site
• Local events at many locations
• 2014 Grand Central Terminal Awareness &
Education Event
• 2014 Social Media Campaign on Facebook,
Instagram & Twitter
Facebook WKD Campaign
March 14, 2013
World Kidney Day Goes Viral!
• Reach: The number of people who saw
content from our page through various
• Viral Line: The number of unique people who
saw a story about our page published by a
• Peak: 229,587 total people reached from
3/9/13- 3/15/13!
Ask the Doctor!
Dr. Leslie Spry, MD, FACP
• Are you concerned about yourself, a friend or
family member? Ask away. Dr. Leslie Spry is
happy to provide answers to any questions.
• Dr. Spry practices consultative nephrology, is
the medical director of the Dialysis Center of
Lincoln in Nebraska, & participates in
research/innovative projects to benefit dialysis
PEERS Lending Support
For those who want more one-on-one support
than a healthcare professional can provide in a
brief office visit…
• A telephone-based peer support program
• Connects people who want support with
someone who has been there
• Helps people adjust to living with any stage
CKD, kidney failure, or a kidney transplant
Seventh Annual Symposium on
Chronic Kidney Disease:
The Cardiac-Kidney-Diabetes Connection
The Roosevelt Hotel, New York City
April 4, 2014
Free CME Programs
Achieving Better Outcomes for Kidney Transplant Recipients:
Optimizing Patient Management
• Available through February 25, 2015
• This web-based interactive virtual patient program will help
participants: 1) consider available immunosuppressive
therapies for kidney transplant recipients; 2) make optimal
clinical decisions based on the needs and comorbidities of
their patients; 3) individualize therapy for kidney transplant
patients; and 4) provide the necessary patient teaching so
that patients are more able to adhere to immunosuppressive
• Approved for 1.5 continuing education clock hours
What is “Living Well With
Kidney Failure?”
• A six-part educational
video series
• Created by the National
Kidney Foundation to
educate patients and
their families about
kidney failure and its
• An update of the popular
“People Like Us” Video
• Caddy
• Letter to Clinician
• Leader’s Guide for
• Educational DVD
• Patient Booklets
• Record of Participation

The National Kidney Foundation’s Kidney Early Evaluation